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2-Bromo-2-Nitropropane-1,3-Doil (Bromopol)Updated a month ago

An antimicrobial preservative that slowly releases carcinogenic formaldehyde into a product over time (see Formaldehyde). People may develop a contact allergy to formaldehyde or to the ingredient itself. The American Society of Contact Dermatitis lists 2-bromo-2-nitropropane-1,3-diol as one of the allergens even in concentrations as low as 0.5%. In the presence of amines (such as triethanolamine, diethanolamine, and morpholine) in a product, 2-bromo-2-nitropropane-1,3-diol can form nitrosamines, which can penetrate the skin and increase the risk of cancer. Longer storage times and higher temperatures increase the amount of formaldehyde released from 2-bromo-2-nitropropane-1,3-diol, which can lead to higher risks of health problems.

Sources:

http://www.ewg.org/skindeep/ingredient/700019/2-BROMO-2-NITROPROPANE-1%2C3-DIOL_%28FORMALDEHYDE_RELEASER%29/#
http://www.safecosmetics.org/get-the-facts/chemicals-of-concern/formaldehyde/
https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr208.pdf
https://www.cancer.org/cancer/cancer-causes/formaldehyde.html
https://www.contactderm.org/i4a/pages/index.cfm?pageID=3563

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