MethylisothiazolinoneUpdated a month ago
Methylchloroisothiazolinone/Methylisothiazolinone (MCI/MI)
A preservative mixture commonly used in cosmetic products, household cleaning products, and industrial applications. Due to its extensive use, the number of allergic reaction cases caused by MCI/MI or MI alone has been increasing. MI was the American Contact Dermatitis Society Contact Allergen of the Year for 2013.
In addition, studies show that prolonged exposure to low levels of MI may have damaging consequences to the developing nervous system.
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056723/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689087/
https://www.contactderm.org/i4a/pages/index.cfm?pageID=3563
http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_145.pdf
https://www.ncbi.nlm.nih.gov/pubmed/16547166
http://jpet.aspetjournals.org/content/317/3/1320